Pharmaceutical Research - Academic Collaborations: An Insider’s Perspective

IF 3.5 3区医学 Q2 CHEMISTRY, MEDICINAL

ACS Medicinal Chemistry Letters Pub Date : 2025-04-11 DOI:10.1021/acsmedchemlett.5c0008310.1021/acsmedchemlett.5c00083

Stevan W Djuric*,

引用次数: 0

Abstract

A constant pressure on the pharmaceutical industry is the need to develop new therapeutics in a more cost-effective and timely manner. In this letter, I describe the potential that the development and implementation of enabling chemistry technology has for reducing cycle time and cost of goods. Several of these innovations were produced through industry and academic collaborations in which complementary areas of expertise were brought to the table.

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药物研究-学术合作：内部人士的观点

制药业面临的一个持续压力是需要以更具成本效益和更及时的方式开发新疗法。在这封信中，我描述了开发和实施使能化学技术在减少产品周期时间和成本方面的潜力。其中一些创新是通过工业和学术合作产生的，在这种合作中，互补的专业领域被带到桌面上。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Medicinal Chemistry Letters CHEMISTRY, MEDICINAL-

CiteScore

7.30

自引率

2.40%

发文量

328

审稿时长

1 months

期刊介绍： ACS Medicinal Chemistry Letters is interested in receiving manuscripts that discuss various aspects of medicinal chemistry. The journal will publish studies that pertain to a broad range of subject matter, including compound design and optimization, biological evaluation, drug delivery, imaging agents, and pharmacology of both small and large bioactive molecules. Specific areas include but are not limited to: Identification, synthesis, and optimization of lead biologically active molecules and drugs (small molecules and biologics) Biological characterization of new molecular entities in the context of drug discovery Computational, cheminformatics, and structural studies for the identification or SAR analysis of bioactive molecules, ligands and their targets, etc. Novel and improved methodologies, including radiation biochemistry, with broad application to medicinal chemistry Discovery technologies for biologically active molecules from both synthetic and natural (plant and other) sources Pharmacokinetic/pharmacodynamic studies that address mechanisms underlying drug disposition and response Pharmacogenetic and pharmacogenomic studies used to enhance drug design and the translation of medicinal chemistry into the clinic Mechanistic drug metabolism and regulation of metabolic enzyme gene expression Chemistry patents relevant to the medicinal chemistry field.