Pain Reduction in Linzagolix-Treated Patients With Uterine Fibroids: A Secondary Mediation Analysis of the PRIMROSE 1 and 2 Phase 3 Trials

BJOG: An International Journal of Obstetrics & Gynaecology Pub Date : 2025-05-06 DOI:10.1111/1471-0528.18190

Sven Becker, Marie-Madelaine Dolmans, Francisco Carmona Herrera, Felice Petraglia, Stefan P. Renner, Raluca Ionescu-Ittu, Julien St-Pierre, Mitra Boolell, Elke Bestel, Satoshi Hori, Jacques Donnez

引用次数: 0

Abstract

Among women with uterine fibroids (UFs), we assess the extent to which the linzagolix effect on pain alleviation is explained by its effect on reducing heavy menstrual bleeding (HMB) and fibroid volume (FV).

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林扎戈利治疗的子宫肌瘤患者疼痛减轻：PRIMROSE 1期和2期3期试验的二次中介分析

在患有子宫肌瘤（UFs）的女性中，我们评估了林扎哥利克斯减轻疼痛的作用在多大程度上是通过其减少月经大量出血（HMB）和肌瘤体积（FV）的作用来解释的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BJOG: An International Journal of Obstetrics & Gynaecology

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