A Dynamic Double-Flow Gut-On-Chip Model for Predictive Absorption Studies In Vitro (Adv. Mater. Technol. 9/2025)

IF 6.4 3区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

Advanced Materials Technologies Pub Date : 2025-05-05 DOI:10.1002/admt.202570051

Maria Elisabetta Federica Palamà, Maurizio Aiello, Gergő Borka, Jacopo Furci, Ilaria Parodi, Giuseppe Firpo, Silvia Scaglione

引用次数: 0

Abstract

Gut-On-Chip Models

The human gut is essential in digestion, drug absorption, and overall health: the accurate in vitro modelling of the human gut represents a necessary milestone in drug development and disease treatment. In article number 2401661, Silvia Scaglione and co-workers present an innovative gut-on-chip based on the MIVO millifluidic device that faithfully mimics the human intestinal environment, paving the way for more precise therapeutic research and drug discovery.

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一种用于体外预测吸收研究的动态双流芯片肠道模型（Adv. Mater.）。抛光工艺。9/2025)

人体肠道对消化、药物吸收和整体健康至关重要：准确的人体肠道体外模型代表了药物开发和疾病治疗的必要里程碑。在2401661号文章中，Silvia Scaglione及其同事展示了一种基于MIVO微流体装置的创新肠道芯片，该装置可以真实地模拟人类肠道环境，为更精确的治疗研究和药物发现铺平了道路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advanced Materials Technologies Materials Science-General Materials Science

CiteScore

10.20

自引率

4.40%

发文量

566

期刊介绍： Advanced Materials Technologies Advanced Materials Technologies is the new home for all technology-related materials applications research, with particular focus on advanced device design, fabrication and integration, as well as new technologies based on novel materials. It bridges the gap between fundamental laboratory research and industry.