Microcrystals in structural biology: small samples, big insights

IF 2.9 2区材料科学 Q2 CHEMISTRY, MULTIDISCIPLINARY

IUCrJ Pub Date : 2025-05-01 DOI:10.1107/S2052252525003653

Dominik Oberthür

引用次数: 0

Abstract

Microcrystals are transforming structural biology by enabling high-resolution structures and time-resolved insights from samples once deemed too small. This commentary highlights recent advances in microfocus X-ray and MicroED methods, emphasizing their growing role as powerful and complementary tools in modern macromolecular crystallography.

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结构生物学中的微晶体：小样本，大见解

微晶体通过实现高分辨率结构和从曾经被认为太小的样本中获得时间分辨率的见解，正在改变结构生物学。这篇评论强调了微聚焦x射线和MicroED方法的最新进展，强调了它们在现代大分子晶体学中作为强大和补充工具的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

IUCrJ CHEMISTRY, MULTIDISCIPLINARYCRYSTALLOGRAPH-CRYSTALLOGRAPHY

CiteScore

7.50

自引率

5.10%

发文量

审稿时长

10 weeks

期刊介绍： IUCrJ is a new fully open-access peer-reviewed journal from the International Union of Crystallography (IUCr). The journal will publish high-profile articles on all aspects of the sciences and technologies supported by the IUCr via its commissions, including emerging fields where structural results underpin the science reported in the article. Our aim is to make IUCrJ the natural home for high-quality structural science results. Chemists, biologists, physicists and material scientists will be actively encouraged to report their structural studies in IUCrJ.