Photosensitized Imino-Sulfamoylation of Alkenes with Oxime Carbamates

IF 4.9 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Letters Pub Date : 2025-05-01 DOI:10.1021/acs.orglett.5c01128

Ai-Lian Wang, Huan-Huan Zhao, Hao-Wen Jiang, Peng-Fei Xu

引用次数: 0

Abstract

In this study, we have devised a strategy that employs oxime carbamate as a bifunctional diamination reagent in combination with SO₂ to realize imino-sulfamoylation of alkenes. This protocol is characterized by its mild conditions, operational simplicity, and metal-free nature, while demonstrating broad functional group tolerance for alkenes. Furthermore, the application of this method provides an accessible route to a diverse range of β-amino sulfonamide derivatives.

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烯与氨基甲酸肟的光敏亚胺磺化反应

在这项研究中，我们设计了一种策略，利用氨基甲酸肟作为双功能二胺化试剂与SO2结合，实现烯烃的亚胺磺化。该协议的特点是其温和的条件，操作简单，无金属性质，同时显示出广泛的官能团对烯烃的耐受性。此外，该方法的应用为多种β-氨基磺酰胺衍生物提供了一条可行的途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Organic Letters 化学-有机化学

CiteScore

9.30

自引率

11.50%

发文量

1607

审稿时长

1.5 months

期刊介绍： Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.