Unraveling Spiroplasma eriocheiris: Morphological motility, virulence mechanisms, and host defense strategies in crustacean pathogenesis

IF 3.9 1区农林科学 Q1 FISHERIES

Aquaculture Pub Date : 2025-04-15 DOI:10.1016/j.aquaculture.2025.742580

Siyuan Zhang , Jiaxin Chen , Yalan Jiang , Yan Li , Chenbin Zhu , Yujun Tang , Yaqi Wang , Hong Huang , Keming Zhong , Yingrui Xiong , Jiaofeng Peng , Peng Liu

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Abstract

Spiroplasma eriocheiris, a helical, wall-less prokaryote belonging to the class Mollicutes, presents a significant threat to crustacean aquaculture. This pathogen is particularly associated with tremor disease in Eriocheir sinensis, the Chinese mitten crab, resulting in substantial economic losses. Despite being the first spiroplasma identified in crustaceans, our comprehension of S. eriocheiris pathogenesis remains incomplete. This review synthesizes current knowledge regarding S. eriocheiris, focusing on its distinctive morphology and motility, the contribution of virulence factors to infectivity, and the intricate interplay between pathogen evasion strategies and host immune responses. Furthermore, we discuss advancements in diagnostic and therapeutic approaches, offering perspectives for future research directions aimed at mitigating the impact of this economically important pathogen.

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揭示毛鳞螺原体：形态运动、毒力机制和宿主防御策略在甲壳类动物发病机制中的作用

毛鳞螺原体是一种螺旋状、无壁的原核生物，是甲壳类水产养殖的重要威胁。这种病原体与中华绒螯蟹（中华绒螯蟹）的震颤病特别相关，造成重大经济损失。尽管这是甲壳类动物中发现的第一个螺旋体，但我们对羊角弧菌发病机制的理解仍然不完整。本文综述了目前关于毛毛链球菌的知识，重点介绍了其独特的形态和运动，毒力因素对感染性的贡献，以及病原体逃避策略与宿主免疫反应之间复杂的相互作用。此外，我们讨论了诊断和治疗方法的进展，为未来的研究方向提供了前景，旨在减轻这种经济上重要的病原体的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Aquaculture 农林科学-海洋与淡水生物学

CiteScore

8.60

自引率

17.80%

发文量

1246

审稿时长

56 days

期刊介绍： Aquaculture is an international journal for the exploration, improvement and management of all freshwater and marine food resources. It publishes novel and innovative research of world-wide interest on farming of aquatic organisms, which includes finfish, mollusks, crustaceans and aquatic plants for human consumption. Research on ornamentals is not a focus of the Journal. Aquaculture only publishes papers with a clear relevance to improving aquaculture practices or a potential application.