{"title":"Review questions sustained efficacy of esketamine in treatment-resistant depression","authors":"","doi":"10.1002/pu.31310","DOIUrl":null,"url":null,"abstract":"<p>Results of a systematic review and meta-analysis suggest that esketamine has only modest efficacy in the treatment of adults with treatment-resistant depression, with initial improvement diminishing after the first few days. The results also suggest no effect of esketamine on suicidality.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 6","pages":"3"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Brown University Psychopharmacology Update","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/pu.31310","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Results of a systematic review and meta-analysis suggest that esketamine has only modest efficacy in the treatment of adults with treatment-resistant depression, with initial improvement diminishing after the first few days. The results also suggest no effect of esketamine on suicidality.
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