Hemoglobina preoperatoria como factor predictivo de morbilidad intrahospitalaria y mortalidad a 5 años en el cáncer colorrectal

IF 0.9 Q3 ANESTHESIOLOGY

Revista Espanola de Anestesiologia y Reanimacion Pub Date : 2025-02-17 DOI:10.1016/j.redar.2024.501723

A. Herrero García , S.E. Denis Filippini , A. de la Fuente , E. Choolani Bhojwani , J. Sánchez González , M. Bailón Cuadrado , S. Veleda Belanche , V. Simó Fernández , J.A. García Erce , C. Aldecoa Álvarez-Santullano

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Abstract

Background

Colorectal cancer (CRC) is the third most diagnosed cancer worldwide. Preoperative anaemia is common in CRC patients undergoing surgery.

Objective

This study assesses the prevalence of preoperative anaemia and its impact on postoperative outcomes, and aims to establish a cut-off point for increased morbidity and mortality in a large prospective single centre cohort.

Methods

We conducted a retrospective cohort study of 1105 CRC patients (2014-2021). Anaemia was defined as per WHO criteria. Multivariate logistic regression and Kaplan-Meier survival analyses were used. The statistical significance level was set at < .05.

Results

Preoperative anaemia was present in 45.3% of patients, and was associated with a higher incidence of perioperative complications (OR: 2.76; P = .011) and lower 5-year survival (73% vs 87%, p < .001.

Discussion/conclusions

Preoperative anaemia, even when mild, is associated with a higher rate of complications, longer hospital stay, and a greater risk of 5-year mortality.

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术前血红蛋白作为结肠直肠癌5年院内发病率和死亡率的预测因素

结直肠癌（CRC）是全球第三大确诊癌症。术前贫血在结直肠癌手术患者中很常见。目的：本研究评估术前贫血的患病率及其对术后预后的影响，旨在建立一个大型前瞻性单中心队列中发病率和死亡率增加的分界点。方法对2014-2021年1105例结直肠癌患者进行回顾性队列研究。贫血是根据世卫组织标准定义的。采用多元逻辑回归和Kaplan-Meier生存分析。统计学显著性水平设为<；. 05。结果45.3%的患者存在术前贫血，且伴有较高的围手术期并发症发生率(OR: 2.76；P = 0.011)和更低的5年生存率(73% vs 87%, P <；措施。讨论/结论：术后贫血，即使是轻度贫血，也与较高的并发症发生率、较长的住院时间和较高的5年死亡率相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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