Visualizing ozone fluctuations employing a fluorescent probe in stimulated-epilepsy cell models

IF 4.3 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-04-28 DOI:10.1039/d4cc06310d

Jian Zhang, Yu Duan, Chang Liu, Mingyue Zhang, Heng Liu, Xingchen Ming, Yong Li, Xiaoyun Jiao, Xu Wang, Bo Tang

引用次数: 0

Abstract

BID-Ozo, a mitochondrial-targeted fluorescence probe specifically designed to detect endogenous ozone (O₃) was developed. A significant increase in intracellular O₃ was observed in PC12 cells stimulated with high concentrations of glutamate (Glu), which is used to model epilepsy.

查看原文本刊更多论文

在刺激性癫痫细胞模型中使用荧光探针可视化臭氧波动

BID-Ozo是一种专门用于检测内源性臭氧（O₃）的线粒体靶向荧光探针。用高浓度谷氨酸（Glu）刺激PC12细胞，观察到细胞内O₃显著增加。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.