ROS-Responsive Microneedle Patches Enable Peri-Lacrimal Gland Therapeutic Administration for Long-Acting Therapy of Sjögren's Syndrome-Related Dry Eye (Adv. Sci. 16/2025)

IF 14.3 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Advanced Science Pub Date : 2025-04-24 DOI:10.1002/advs.202570111

Jingqing Mu, Xiangyu Ding, Yapeng Song, Baoyue Mi, Xiaolong Fang, Baihua Chen, Bin Yao, Xuguang Sun, Xiaoyong Yuan, Shutao Guo, Xia Hua

引用次数: 0

Abstract

Microneedle Patches for Dry Eye Treatment

The cover illustrates an intelligent gel-based microneedle (MN) patch designed for targeted drug delivery to the lacrimal gland. This innovative patch facilitates sustained drug release in a reactive oxygen species (ROS)-responsive manner, ensuring precise therapeutic action. Additionally, the patch features a separable base that operates in a temperature-responsive fashion, enhancing user comfort and ease of application. More details can be found in article number 2409562 by Xiaoyong Yuan, Shutao Guo, Xia Hua, and co-workers.

Abstract Image

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ros反应微针贴片使泪腺周围治疗给药长期治疗Sjögren综合征相关性干眼症（Adv. Sci. 16/2025）

用于干眼症治疗的微针贴片该封面展示了一种基于凝胶的智能微针（MN）贴片，设计用于靶向药物输送到泪腺。这种创新的贴片促进以活性氧（ROS）反应的方式持续释放药物，确保精确的治疗作用。此外，该贴片具有可分离的基础，以温度响应方式操作，增强用户舒适度和易于应用。更多细节可以在2409562号文章中找到，作者是袁晓勇、郭树涛、夏华和同事。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advanced Science CHEMISTRY, MULTIDISCIPLINARYNANOSCIENCE &-NANOSCIENCE & NANOTECHNOLOGY

CiteScore

18.90

自引率

2.60%

发文量

1602

审稿时长

1.9 months

期刊介绍： Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.