Animal models of epilepsy after ischemic stroke

Abstract

Stroke ranks among the foremost causes of disability and mortality globally, with ischemic stroke (IS) being the most prevalent subtype. Post-stroke epilepsy (PSE) represents a significant and common complication following a stroke, imposing substantial burdens on patients, their families, and society at large. Establishing a reliable animal model is crucial for investigating the mechanisms and potential treatments for PSE. This article offers a review of studies pertaining to animal models of epilepsy subsequent to ischemic stroke.