{"title":"Fifty-Four Tablets Too Many: A Case Report of Amlodipine and Losartan Overdose","authors":"Nishan Uprety, Bishal Bhandari, Vinayak Dhungana, Sulav Neupane, Sunischit Chandra Neupane, Sujan Tamang, Samiksha Acharya","doi":"10.1002/ccr3.70457","DOIUrl":null,"url":null,"abstract":"<p>Overdoses of widely used cardiovascular drugs calcium channel blockers and angiotensin receptor blockers cause severe hemodynamic instability. Timely management with hyperinsulinemia–euglycemia therapy, vasopressors, and calcium gluconate is critical. Enhanced clinical vigilance, prompt intervention, and long-term care, including psychological evaluation, are essential to address underlying factors and prevent recurrence of overdoses.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 4","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70457","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.70457","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Overdoses of widely used cardiovascular drugs calcium channel blockers and angiotensin receptor blockers cause severe hemodynamic instability. Timely management with hyperinsulinemia–euglycemia therapy, vasopressors, and calcium gluconate is critical. Enhanced clinical vigilance, prompt intervention, and long-term care, including psychological evaluation, are essential to address underlying factors and prevent recurrence of overdoses.
期刊介绍:
Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).