Cobalt-catalyzed esterification of organohalides with carbon monoxide

IF 6.5 1区化学 Q2 CHEMISTRY, PHYSICAL

Journal of Catalysis Pub Date : 2025-04-18 DOI:10.1016/j.jcat.2025.116154

Heng Yang, Yan Jiao, Guodong Zhang, Pan Gao, Feng Chen

引用次数: 0

Abstract

Esters are fundamental compounds in materials science, medicinal chemistry, and organic synthesis. Numerous synthetic methods have been developed to construct ester functional groups. The transition metal-catalyzed carbonylation of aryl halides with alcohols is well-established, with palladium catalysts being the most commonly used. However, the development of non-noble metal-based catalysts for carbonylation reactions has become attractive due to their cost-effectiveness. In this study, we report a novel homogeneous cobalt-catalyzed system for the carbonylation of aryl bromides and aryl chlorides with alkyl halides directly. Notably, this methodology efficiently prepares specialized esters using inexpensive alkyl halides, offering a more economical alternative to using the corresponding alcohols.

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钴催化有机卤化物与一氧化碳的酯化反应

酯是材料科学、药物化学和有机合成中的基本化合物。许多合成方法被开发来构建酯官能团。过渡金属催化芳基卤化物与醇的羰基化反应是公认的，钯催化剂是最常用的。然而，羰基化反应的非贵金属催化剂因其成本效益而备受关注。在这项研究中，我们报告了一种新的均相钴催化体系，用于芳基溴和芳基氯直接与烷基卤化物羰基化。值得注意的是，这种方法有效地制备专用酯使用廉价的烷基卤化物，提供了一个更经济的替代使用相应的醇。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Catalysis 工程技术-工程：化工

CiteScore

12.30

自引率

5.50%

发文量

447

审稿时长

31 days

期刊介绍： The Journal of Catalysis publishes scholarly articles on both heterogeneous and homogeneous catalysis, covering a wide range of chemical transformations. These include various types of catalysis, such as those mediated by photons, plasmons, and electrons. The focus of the studies is to understand the relationship between catalytic function and the underlying chemical properties of surfaces and metal complexes. The articles in the journal offer innovative concepts and explore the synthesis and kinetics of inorganic solids and homogeneous complexes. Furthermore, they discuss spectroscopic techniques for characterizing catalysts, investigate the interaction of probes and reacting species with catalysts, and employ theoretical methods. The research presented in the journal should have direct relevance to the field of catalytic processes, addressing either fundamental aspects or applications of catalysis.