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Inside Back Cover: Molecular Diagnosis and Therapy of Dental Caries by Oral Microbiome-Selective Aggregation-Induced Photosensitivity

IF 13.9 Q1 CHEMISTRY, MULTIDISCIPLINARY
Aggregate (Hoboken, N.J.) Pub Date : 2025-04-17 DOI:10.1002/agt2.70035
Yandi Zhang, Wenjun Wang, Xiaoru Yang, Xuanmeng An, Xiaoyi Liu, Weiwei Zhao, Lina Zhu, Ting Wang, Ying Wang, Yi Chen, Junkun Feng, Jinlong Shao, Xuedong Zhou, Ben Zhong Tang, Shaohua Ge, Jianhua Li
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Abstract

This study introduces an aggregation-induced emission probe, MeOTpy, for instant molecular detection and photodynamic treatment of dental caries. MeOTpy exhibited bright fluorescence upon binding to cariogenic pathogens and generating reactive oxygen species under white light irradiation. This aggregation-induced photosensitivity enables rapid assessment of carious disease in human dental plaque samples and prevented dental caries on rat pups (e733).

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内封底：利用口腔微生物群选择性聚集诱导的光敏性进行龋齿的分子诊断和治疗
本研究介绍了一种聚合诱导发射探针MeOTpy，用于即时分子检测和光动力治疗龋病。在白光照射下，MeOTpy与致龋病原菌结合并产生活性氧，表现出明亮的荧光。这种聚集诱导的光敏性可以快速评估人类牙菌斑样本中的龋齿疾病，并防止大鼠幼崽龋齿（e733）。
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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来源期刊
Aggregate (Hoboken, N.J.)
Aggregate (Hoboken, N.J.)
CiteScore
17.40
自引率
0.00%
发文量
0
审稿时长
7 weeks
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