Pulmonary complications after intrathecal morphine administration: a systematic review and meta-analysis with meta-regression and trial sequential analysis

IF 7.5 1区医学 Q1 ANESTHESIOLOGY

Anaesthesia Pub Date : 2025-04-16 DOI:10.1111/anae.16606

Kariem El-Boghdadly, Yves Renard, Jean-Benoit Rossel, Eleni Moka, Thomas Volk, Narinder Rawal, Cécile Jaques, Marta Szyszko, Eric Albrecht

引用次数: 0

Abstract

Intrathecal morphine provides effective postoperative analgesia, but there are concerns about potential pulmonary complications influencing peri-operative management. We aimed to determine whether there is an association between intrathecal morphine administration and pulmonary complications after non-obstetric surgery. We also aimed to determine whether there was a dose-dependent effect on pulmonary complications.

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鞘内注射吗啡后的肺部并发症：一项系统回顾和荟萃分析，包括荟萃回归和试验序列分析

鞘内吗啡可提供有效的术后镇痛，但人们担心潜在的肺部并发症会影响围手术期的管理。我们旨在确定鞘内吗啡给药与非产科手术后肺部并发症之间是否存在关联。我们还旨在确定肺部并发症是否与剂量有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Anaesthesia 医学-麻醉学

CiteScore

21.20

自引率

9.30%

发文量

300

审稿时长

6 months

期刊介绍： The official journal of the Association of Anaesthetists is Anaesthesia. It is a comprehensive international publication that covers a wide range of topics. The journal focuses on general and regional anaesthesia, as well as intensive care and pain therapy. It includes original articles that have undergone peer review, covering all aspects of these fields, including research on equipment.