Correction: Targeting SOST using a small‑molecule compound retards breast cancer bone metastasis

Abstract

Correction: Mol Cancer 21, 228 (2022)

https://doi.org/10.1186/s12943-022-01697-4

Following publication of the original article [1], the authors dentified an inadvertent image duplication in the supplementary Figure S2-C which occurred during the figure preparation process and wish to formally request an erratum to rectify this issue. The updated Figure S2-C can be downloaded from the link provided in the Additional file 1 below.

1. Sun L, Zhang Y, Chen G, et al. Targeting SOST using a small-molecule compound retards breast cancer bone metastasis. Mol Cancer. 2022;21:228. https://doi.org/10.1186/s12943-022-01697-4.

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Author notes

1. Lisha Sun, Yixiao Zhang, Guanglei Chen and Yaoting Ji contributed equallyto this work.

Authors and Affiliations

1. Department of Oncology, Innovative Cancer Drug Research and Engineering Center of Liaoning Province, Cancer Stem Cell and Translation Medicine Lab, Shengjing Hospital of China Medical University, Shenyang, China

   Lisha Sun, Yixiao Zhang, Guanglei Chen, Qingtian Ma, Xinbo Qiao, Jiawen Bu, Xudong Zhu, Xiaoying Zhang, Xiaofan Jiang, Chao Liu, Xinnan Li & Caigang Liu

2. Department of Urology Surgery, Shengjing Hospital of China Medical University, Shenyang, China

   Yixiao Zhang

3. The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei‑MOST) and Key Laboratory for Oral Biomedicine of Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China

   Yaoting Ji

4. Dalian Institute of Chemical Physics, Chinese Academy of Science, Dalian, China

   Sijin Wu

5. Key Laboratory of Structure‑Based Drug Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China

   Lin Zhou & Yang Liu

6. School of Bioengineering, Dalian University of Technology, Dalian, China

   Yongliang Yang

Authors

1. Lisha SunView author publications

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2. Yixiao ZhangView author publications

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7. Sijin WuView author publications

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15. Yang LiuView author publications

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16. Yongliang YangView author publications

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Corresponding authors

Correspondence to Sijin Wu or Caigang Liu.

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12943_2025_2322_MOESM1_ESM.docx

Supplementary Material 1: Additional file 1: Fig. S1. Survival analysis of SOST expression in differentsubgroups of breast cancer patients. Fig. S2. SOST knockdown inhibitsthe proliferation and migration of SCP2 cells in vitro. Fig. S3. Correlationanalysis of STAT3 expression with RAS and TGF-β/SMADs. Fig. S4. BLIanalysis of 35 small-molecule compounds targeting SOST, except for 3insoluble small-molecule compounds. Fig. S5. Other candidates thattargeting SOST protein. Fig. S6. The cytotoxicity of S6 compound againstbreast cancer cells. Fig. S7. The safety profile of S6 in the vital organs oftumor-bearing mice. Table S1. Single concentration screening of smallmolecules.Table S2. The results of the multi-concentration gradientassays were calculated

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Sun, L., Zhang, Y., Chen, G. et al. Correction: Targeting SOST using a small‑molecule compound retards breast cancer bone metastasis. Mol Cancer 24, 117 (2025). https://doi.org/10.1186/s12943-025-02322-w

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• Published: 16 April 2025

• DOI: https://doi.org/10.1186/s12943-025-02322-w

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