CRISPR-StAR to transform in vivo functional genomic screening

IF 72.5 1区医学 Q1 ONCOLOGY

Nature Reviews Cancer Pub Date : 2025-04-16 DOI:10.1038/s41568-025-00818-7

Christopher Lowden

引用次数: 0

Abstract

In this Tools of the Trade article, Christopher Lowden describes the development and use of CRISPR-StAR, which leverages internal controls to overcome experimental noise for improved in vivo functional genomic screens.

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CRISPR-StAR转化体内功能基因组筛选

在这篇贸易工具文章中，Christopher Lowden描述了CRISPR-StAR的开发和使用，该技术利用内部控制来克服实验噪声，以改进体内功能基因组筛选。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Cancer 医学-肿瘤学

CiteScore

111.90

自引率

0.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Cancer, a part of the Nature Reviews portfolio of journals, aims to be the premier source of reviews and commentaries for the scientific communities it serves. The correct abbreviation for abstracting and indexing purposes is Nat. Rev. Cancer. The international standard serial numbers (ISSN) for Nature Reviews Cancer are 1474-175X (print) and 1474-1768 (online). Unlike other journals, Nature Reviews Cancer does not have an external editorial board. Instead, all editorial decisions are made by a team of full-time professional editors who are PhD-level scientists. The journal publishes Research Highlights, Comments, Reviews, and Perspectives relevant to cancer researchers, ensuring that the articles reach the widest possible audience due to their broad scope.