MDIPID: Microbiota-drug interaction and disease phenotype interrelation database

IF 23.7 Q1 MICROBIOLOGY

iMeta Pub Date : 2025-03-21 DOI:10.1002/imt2.70019

Jiayi Yin, Hui Ma, Yuting Qi, Qingwei Zhao, Su Zeng, Fengcheng Li, Feng Zhu

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引用次数: 0

Abstract

The intricate bidirectional relationships among microbiota, microbial proteins, drugs, and diseases are essential for advancing precision medicine and minimizing adverse drug reactions. However, there are currently no data resources that comprehensively describe these valuable interactions. Therefore, the Microbiota-Drug Interaction and Disease Phenotype Interrelation Database (MDIPID) database was developed in this study. MDIPID is distinctive in its ability to elucidate the complex interactions among microbiota, microbial proteins, drugs/substances, and disease phenotypes, thereby providing a comprehensive interconnected network that facilitates the identification of microbial therapy targets and advances personalized medicine. This comprehensive resource is expected to become a popular repository for researchers aiming to identify microbial therapeutic targets, predict drug efficacy, and develop new therapies, thereby facilitating the advancement of personalized medicine. MDIPID can be accessed free without any login requirement at: https://idrblab.org/mdipid/.

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MDIPID：微生物-药物相互作用和疾病表型相互关系数据库

微生物群、微生物蛋白、药物和疾病之间复杂的双向关系对于推进精准医疗和减少药物不良反应至关重要。然而，目前还没有全面描述这些有价值的相互作用的数据资源。因此，本研究建立了微生物-药物相互作用和疾病表型相互关系数据库（MDIPID）。MDIPID的独特之处在于它能够阐明微生物群、微生物蛋白、药物/物质和疾病表型之间复杂的相互作用，从而提供一个全面的相互关联的网络，促进微生物治疗靶点的识别和推进个性化医疗。这一综合资源有望成为旨在确定微生物治疗靶点、预测药物疗效和开发新疗法的研究人员的热门资源库，从而促进个性化医疗的进步。MDIPID可以免费访问，无需任何登录要求：https://idrblab.org/mdipid/。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

iMeta

CiteScore

10.80

自引率

0.00%

发文量