Pharmacodynamic biomarkers responsive to mutant huntingtin lowering in a Huntington's disease mouse model

IF 5.1 2区医学 Q1 NEUROSCIENCES

Neurobiology of Disease Pub Date : 2025-04-09 DOI:10.1016/j.nbd.2025.106906

Deanna M. Marchionini , Stef De Lombaerde , Joëlle van Rijswijk , Franziska Zajicek , Liesbeth Everix , Alan Miranda , Mari J. Aaltonen , Carleen M. Kluger , Thomas Wild , Aglaia Kakoulidou , Jannis Gundelach , Tim Fieblinger , Joachim Fentz , Jim Rosinski , John Obenauer , Jonathan R. Greene , Longbin Liu , Ignacio Munoz-Sanjuan , Marleen Verhoye , Jeroen Verhaeghe , Daniele Bertoglio

引用次数: 0

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在亨廷顿氏病小鼠模型中，对突变亨廷顿蛋白降低有反应的药效学生物标志物

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来源期刊

Neurobiology of Disease 医学-神经科学

CiteScore

11.20

自引率

3.30%

发文量

270

审稿时长

76 days

期刊介绍： Neurobiology of Disease is a major international journal at the interface between basic and clinical neuroscience. The journal provides a forum for the publication of top quality research papers on: molecular and cellular definitions of disease mechanisms, the neural systems and underpinning behavioral disorders, the genetics of inherited neurological and psychiatric diseases, nervous system aging, and findings relevant to the development of new therapies.