Neural control of male sexual behaviours

IF 12.1 1区医学 Q1 UROLOGY & NEPHROLOGY

Nature Reviews Urology Pub Date : 2025-04-09 DOI:10.1038/s41585-025-01034-6

Maria Chiara Masone

引用次数: 0

Abstract

Copulatory behaviour in rodents follows a stereotypical sequence of actions consisting in mounting, intromission and ejaculation. Different brain regions, including the nucleus accumbens (NAc), and different neurotransmitters, particularly dopamine (DA) and acetylcholine (ACh), have been shown to have a role in regulating copulatory behaviours, but the exact neural mechanisms regulating the transitions from mounting to intromission to ejaculation remain elusive.

A new study published in Neuron investigates how ACh modulates DA dynamics in different subregions of NAc to regulate male sexual behaviours.

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男性性行为的神经控制

啮齿类动物的交配行为遵循一个典型的动作序列，包括爬上、插入和射精。不同的大脑区域，包括伏隔核（NAc）和不同的神经递质，特别是多巴胺（DA）和乙酰胆碱（ACh），已被证明在调节交配行为中发挥作用，但调节从积累到射精过渡的确切神经机制仍然难以捉摸。发表在《神经元》杂志上的一项新研究调查了乙酰胆碱如何调节NAc不同亚区的DA动态来调节男性的性行为。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Urology 医学-泌尿学与肾脏学

CiteScore

12.50

自引率

2.60%

发文量

123

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Urology is part of the Nature Reviews portfolio of journals.Nature Reviews' basic, translational and clinical content is written by internationally renowned basic and clinical academics and researchers. This journal targeted readers in the biological and medical sciences, from the postgraduate level upwards, aiming to be accessible to professionals in any biological or medical discipline. The journal features authoritative In-depth Reviews providing up-to-date information on topics within a field's history and development. Perspectives, News & Views articles, and the Research Highlights section offer topical discussions and opinions, filtering primary research from various medical journals. Covering a wide range of subjects, including andrology, urologic oncology, and imaging, Nature Reviews provides valuable insights for practitioners, researchers, and academics within urology and related fields.