{"title":"Microultrasonography-guided prostate cancer biopsy","authors":"Maria Chiara Masone","doi":"10.1038/s41585-025-01033-7","DOIUrl":null,"url":null,"abstract":"<p>The incorporation of magnetic resonance imaging (MRI) into the prostate cancer diagnostic workflow has substantially improved detection of clinically significant prostate cancer (defined as Gleason grade group ≥2) but also has some limitations, such as the need for sophisticated imaging facilities that are not accessible in every institution. Microultrasonography, which has an incredibly high resolution (70-μm resolution), could be a valid alternative to MRI in prostate biopsy.</p><p>The OPTIMUM randomized controlled trial was conducted to assess the non-inferiority of microultrasonography-guided biopsy compared with MRI plus conventional ultrasonography fusion-guided biopsy for the detection of clinically significant prostate cancer in biopsy-naive men, and the results were published in <i>JAMA</i>.</p>","PeriodicalId":19088,"journal":{"name":"Nature Reviews Urology","volume":"99 1","pages":""},"PeriodicalIF":12.1000,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Reviews Urology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41585-025-01033-7","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The incorporation of magnetic resonance imaging (MRI) into the prostate cancer diagnostic workflow has substantially improved detection of clinically significant prostate cancer (defined as Gleason grade group ≥2) but also has some limitations, such as the need for sophisticated imaging facilities that are not accessible in every institution. Microultrasonography, which has an incredibly high resolution (70-μm resolution), could be a valid alternative to MRI in prostate biopsy.
The OPTIMUM randomized controlled trial was conducted to assess the non-inferiority of microultrasonography-guided biopsy compared with MRI plus conventional ultrasonography fusion-guided biopsy for the detection of clinically significant prostate cancer in biopsy-naive men, and the results were published in JAMA.
期刊介绍：
Nature Reviews Urology is part of the Nature Reviews portfolio of journals.Nature Reviews' basic, translational and clinical content is written by internationally renowned basic and clinical academics and researchers. This journal targeted readers in the biological and medical sciences, from the postgraduate level upwards, aiming to be accessible to professionals in any biological or medical discipline.
The journal features authoritative In-depth Reviews providing up-to-date information on topics within a field's history and development. Perspectives, News & Views articles, and the Research Highlights section offer topical discussions and opinions, filtering primary research from various medical journals.
Covering a wide range of subjects, including andrology, urologic oncology, and imaging, Nature Reviews provides valuable insights for practitioners, researchers, and academics within urology and related fields.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
