Management of Trichodysplasia Spinulosa in a Pediatric Kidney Transplant Patient With Topical Cidofovir and Oral Leflunomide.

IF 1.2 4区 医学 Q3 PEDIATRICS
Annika M Hansen, Sonia Mehra, Anneli R Bowen, Joseph Sherbotie, Sarah D Cipriano
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引用次数: 0

Abstract

Background: This case report describes a 10-year-old male with a history of kidney transplantation who developed trichodysplasia spinulosa (TS), a rare skin disorder associated with immunosuppression.

Methods: The patient's condition, characterized by follicular papules and keratinous spines primarily on the face, was managed by a multidisciplinary team.

Results: Treatment involved reducing immunosuppression and administering topical cidofovir alongside oral leflunomide, leading to significant clinical improvement over several months.

Conclusions: This case adds to the literature of TS management and highlights the importance of multidisciplinary care as well as the challenges of treatment accessibility due to insurance limitations.

用局部西多福韦和口服来氟米特治疗小儿肾移植患者的棘层毛囊炎
背景:本病例报告描述了一名有肾移植史的10岁男性,他发展为棘毛结构不良(TS),这是一种罕见的与免疫抑制相关的皮肤病。方法:患者的病情,特点是滤泡丘疹和角状棘主要在脸上,是由一个多学科的团队管理。结果:治疗包括减少免疫抑制和给予局部西多福韦和口服来氟米特,在几个月内导致显著的临床改善。结论:该病例增加了TS管理的文献,突出了多学科护理的重要性,以及由于保险限制而导致的治疗可及性的挑战。
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来源期刊
Pediatric Transplantation
Pediatric Transplantation 医学-小儿科
CiteScore
2.90
自引率
15.40%
发文量
216
审稿时长
3-8 weeks
期刊介绍: The aim of Pediatric Transplantation is to publish original articles of the highest quality on clinical experience and basic research in transplantation of tissues and solid organs in infants, children and adolescents. The journal seeks to disseminate the latest information widely to all individuals involved in kidney, liver, heart, lung, intestine and stem cell (bone-marrow) transplantation. In addition, the journal publishes focused reviews on topics relevant to pediatric transplantation as well as timely editorial comment on controversial issues.
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