The reproductive system and breast metastases - a narrative review and case series of metastases from soft tissue and bone sarcomas in girls.

Abstract

Four cases of girls with metastases of soft tissue or bone sarcomas to the reproductive system or breasts are reported. Two patients had metastases to the breast from rhabdomyosarcoma (RMS) of the limbs, one had metastases to the ovary from RMS of the foot, and one had metastases to the uterine venous plexus from chondrosarcoma of the sacrum. In each case, the appearance of metastases was shown in various imaging methods: ultrasound, magnetic resonance imaging, and computed tomography. A thorough literature review confirmed that only a few cases of soft tissue and bone sarcoma metastasis to the locations of primary interest of this article in girls have been described, especially in the context of reproductive organs. Despite the rare occurrence of this type of metastases, the malignant tumours mentioned above should be considered when differentiating the source. These rare clinical situations are woven into a review of malignant neoplasms' metastases to the reproductive organs and breast.