[Cognitive functions assessment of elderly patients with type 2 diabetes mellitus].

Q3 Medicine

Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova Pub Date : 2025-01-01 DOI:10.17116/jnevro202512503146

A A Akhmedova, F O Ushanova, T Yu Demidova

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引用次数: 0

Abstract

Objective: Comparative assessment of the cognitive status of persons over 60, depending on the presence or absence of type 2 diabetes mellitus (T2DM).

Material and methods: The study included 193 patients, of which 93 had no T2DM and 100 had T2DM. The mean age of patients with T2DM was 73 [68; 78] years vs. 69.2 [64; 75] years in patients without T2DM. The cognitive function was assessed using the McNair and Kahn scale, with scores over 42 indicating cognitive dysfunction and Kahn scale: in the group with T2DM, the average score was 27.0±9.36; in the group without T2DM, it was 22.0±9.60 (p<0.043). The absence of T2DM was negatively correlated with the total score on the scale for assessing the risk of cognitive impairment (p=-0.264, p<0.001). In addition, it was found that age over 75 years was significantly associated with the development of cognitive impairment, regardless of the presence of concomitant T2DM (OR=1.247, CI=95%, 1.112-1.40, p<0.001).

Conclusion: T2DM increases the risk of developing cognitive dysfunction, which should be taken into account in older patients for the timely detection and prevention of its progression.

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老年2型糖尿病患者的认知功能评估。

目的：根据是否患有 2 型糖尿病（T2DM），对 60 岁以上老年人的认知状况进行比较评估：根据是否患有 2 型糖尿病（T2DM），对 60 岁以上老年人的认知状况进行比较评估：研究包括 193 名患者，其中 93 人无 T2DM，100 人有 T2DM。T2DM患者的平均年龄为73 [68; 78]岁，而非T2DM患者的平均年龄为69.2 [64; 75]岁。认知功能采用麦克奈尔和卡恩量表进行评估，得分超过 42 分表示认知功能障碍，卡恩量表：T2DM 患者组的平均得分为（27.0±9.36）分；无 T2DM 患者组的平均得分为（22.0±9.60）分（P0.043）。无 T2DM 与认知障碍风险评估量表的总分呈负相关（p=-0.264，p0.001）。此外，研究还发现，无论是否伴有 T2DM，年龄超过 75 岁都与认知障碍的发生显著相关（OR=1.247，CI=95%，1.112-1.40，p0.001）：T2DM会增加认知功能障碍的发病风险，老年患者应考虑到这一点，以便及时发现并预防认知功能障碍的发展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova 医学-精神病学

CiteScore

1.10

自引率

0.00%

发文量

287

审稿时长

3-6 weeks

期刊介绍： Одно из старейших медицинских изданий России, основанное в 1901 году. Создание журнала связано с именами выдающихся деятелей отечественной медицины, вошедших в историю мировой психиатрии и неврологии, – С.С. Корсакова и А.Я. Кожевникова. Широкий диапазон предлагаемых журналом материалов и разнообразие форм их представления привлекают внимание научных работников и врачей, опытных и начинающих медиков, причем не только неврологов и психиатров, но и специалистов смежных областей медицины.