Short-Term Relief with Upadacitinib: A Case Report of Palmoplantar Pustulosis in a Pediatric Patient.

IF 1.9 4区医学 Q3 DERMATOLOGY

Clinical, Cosmetic and Investigational Dermatology Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI:10.2147/CCID.S494567

Qinchen Gu, Chen Zhang, Zhimin Lin, Yiting Fu, Chen Li, Zhenhua Ying

引用次数: 0

Abstract

Palmoplantar pustulosis (PPP) is a chronic inflammatory skin disease with recurrent erythema, scales, and sterile pustules on the palms and soles. Treating PPP in children is difficult due to limited effective therapies, especially as there's a lack of data on upadacitinib use in children under 12.This article reports a pediatric PPP case. The patient had severe, recurring rashes that affected daily activities. Treated with upadacitinib for two months, she showed a significant therapeutic response.

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乌达帕替尼可短期缓解病情：儿科掌跖脓疱病病例报告

掌跖脓疱病（PPP）是一种慢性炎症性皮肤病，伴有手掌和脚底反复出现红斑、鳞片和无菌脓疱。由于有效的治疗方法有限，治疗儿童PPP很困难，特别是缺乏关于12岁以下儿童使用upadacitinib的数据。本文报告一例小儿PPP病例。患者有严重的反复发作的皮疹，影响了日常活动。经upadacitinib治疗两个月后，患者表现出明显的治疗反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical, Cosmetic and Investigational Dermatology Medicine-Dermatology

CiteScore

2.80

自引率

4.30%

发文量

353

审稿时长

16 weeks

期刊介绍： Clinical, Cosmetic and Investigational Dermatology is an international, peer-reviewed, open access journal that focuses on the latest clinical and experimental research in all aspects of skin disease and cosmetic interventions. Normal and pathological processes in skin development and aging, their modification and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options are key topics for the journal. Patient satisfaction, preference, quality of life, compliance, persistence and their role in developing new management options to optimize outcomes for target conditions constitute major areas of interest. The journal is characterized by the rapid reporting of clinical studies, reviews and original research in skin research and skin care. All areas of dermatology will be covered; contributions will be welcomed from all clinicians and basic science researchers globally.