{"title":"Physiology of pregnancy","authors":"Nancy Ghosh, Kirsty MacLennan","doi":"10.1016/j.mpaic.2025.02.014","DOIUrl":null,"url":null,"abstract":"<div><div>During pregnancy, maternal physiology undergoes continual adaptation. These often-interlinked changes occur in all body systems and are affected by the hormonal influences of the placenta and the mechanical adaptations required to accommodate the developing fetus. These important physiological changes can potentially lead to decompensation in parturients with pre-existing comorbidities. They may also unmask asymptomatic pre-pregnancy disease. A sound knowledge of the expected maternal changes is essential to enable accurate interpretation of physiological and laboratory parameters. This allows for the implementation of robust care planning with the aim of reducing potential complications.</div></div>","PeriodicalId":45856,"journal":{"name":"Anaesthesia and Intensive Care Medicine","volume":"26 4","pages":"Pages 220-226"},"PeriodicalIF":0.2000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anaesthesia and Intensive Care Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1472029925000414","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
During pregnancy, maternal physiology undergoes continual adaptation. These often-interlinked changes occur in all body systems and are affected by the hormonal influences of the placenta and the mechanical adaptations required to accommodate the developing fetus. These important physiological changes can potentially lead to decompensation in parturients with pre-existing comorbidities. They may also unmask asymptomatic pre-pregnancy disease. A sound knowledge of the expected maternal changes is essential to enable accurate interpretation of physiological and laboratory parameters. This allows for the implementation of robust care planning with the aim of reducing potential complications.
期刊介绍:
Anaesthesia and Intensive Care Medicine, an invaluable source of up-to-date information, with the curriculum of both the Primary and Final FRCA examinations covered over a three-year cycle. Published monthly this ever-updating text book will be an invaluable source for both trainee and experienced anaesthetists. The enthusiastic editorial board, under the guidance of two eminent and experienced series editors, ensures Anaesthesia and Intensive Care Medicine covers all the key topics in a comprehensive and authoritative manner. Articles now include learning objectives and eash issue features MCQs, facilitating self-directed learning and enabling readers at all levels to test their knowledge. Each issue is divided between basic scientific and clinical sections. The basic science articles include anatomy, physiology, pharmacology, physics and clinical measurement, while the clinical sections cover anaesthetic agents and techniques, assessment and perioperative management. Further sections cover audit, trials, statistics, ethical and legal medicine, and the management of acute and chronic pain.