Reaction of a non-heme iron-nitrosyl with dioxygen: Decomposition of the ligand through NOD-like activity

Abstract

A high-spin iron(II) nitrosyl, [(TPz)Fe(NO)](ClO4)2, 2 (TPz = Tris(3,5-dimethylpyrazol-1-ylmethyl)amine) was synthesized and characterized structurally. Dioxygen reactivity of complex 2 in acetonitrile solution results in the oxidation of the ligand. Chemical evidence suggests the involvement of a peroxynitrite intermediate in this reaction. Trapping experiment shows the formation of NO2 during the reaction which supports the proposition of the involvement of the peroxynitrite intermediate. This study gives an insight into an alternate possibility from the dioxygen reactivity of metal-nitrosyl leading to NOD activity.