Charles C. Query, Jadwiga Meissner, Maria M. Konarska
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引用次数: 0
Abstract
Splicing of pre-mRNA requires both high fidelity and enormous sequence flexibility, inevitably resulting in aberrant, stalled complexes that must be discarded. A study now describes cryo-EM structures of stalled complexes poised for disassembly, determining aspects of aberrant complex recognition and splicing quality control.