{"title":"A case of lingual lymphoma in a dog treated with oclacitinib.","authors":"Shohei Nishimori, Kumiko Okano, Kazumi Nibe, Masaya Igase, Takuya Mizuno","doi":"10.1292/jvms.24-0432","DOIUrl":null,"url":null,"abstract":"<p><p>Lingual canine T-zone lymphoma (TZL) is a rare form of extranodal canine lymphoma. 7-years and 5 months old, spayed female toy poodle presented with a red swollen mass on the tongue. A punch biopsy of the lesion was conducted, followed by histopathological and immunohistochemical analyses. Despite the absence of a lymph node excisional biopsy, the case was diagnosed as canine lingual TZL. Although there is no established treatment for lingual TZL, treatment often follows TZL protocols. In this case, the tongue lesion improved after the administration of oclacitinib, a drug approved for canine atopic dermatitis. We present this case due to its successful management with oclacitinib, without the use of conventional anticancer therapy.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Veterinary Medical Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1292/jvms.24-0432","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Lingual canine T-zone lymphoma (TZL) is a rare form of extranodal canine lymphoma. 7-years and 5 months old, spayed female toy poodle presented with a red swollen mass on the tongue. A punch biopsy of the lesion was conducted, followed by histopathological and immunohistochemical analyses. Despite the absence of a lymph node excisional biopsy, the case was diagnosed as canine lingual TZL. Although there is no established treatment for lingual TZL, treatment often follows TZL protocols. In this case, the tongue lesion improved after the administration of oclacitinib, a drug approved for canine atopic dermatitis. We present this case due to its successful management with oclacitinib, without the use of conventional anticancer therapy.
期刊介绍:
JVMS is a peer-reviewed journal and publishes a variety of papers on veterinary science from basic research to applied science and clinical research. JVMS is published monthly and consists of twelve issues per year. Papers are from the areas of anatomy, physiology, pharmacology, toxicology, pathology, immunology, microbiology, virology, parasitology, internal medicine, surgery, clinical pathology, theriogenology, avian disease, public health, ethology, and laboratory animal science. Although JVMS has played a role in publishing the scientific achievements of Japanese researchers and clinicians for many years, it now also accepts papers submitted from all over the world.