The use of nanomedicines in the healthcare systems: A policy brief.

IF 2.4 4区 医学 Q3 CHEMISTRY, MEDICINAL
Somayeh Vandghanooni, Mehdi Jaymand, Morteza Eskandani
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Abstract

ObjectiveNanomedicine is the application of nanotechnology to medicine and, therefore, a potentially transformative approach to healthcare. This new and interdisciplinary field has three main applications in diagnostics, controlled/targeted drug delivery, and regenerative medicine. Nanomedicine has a great potential to change human health by advancing diagnosis, prevention and treatment for a wide variety of diseases, including cancer, cardiovascular conditions, and neurological disorders. Despite overwhelming potential, there are some issues impeding the complete integration of nanomedicines into healthcare systems.SignificanceThis policy brief addresses such critical issues to inform and guide decision-making on effectively deploying nanomedicine to improve patient outcomes and advance important public health initiatives. In addition, some prospects were also presented for future.Key findingsThese brand-new nanosystems have some serious drawbacks in regard to safety, efficacy, and regulatory compliance, not to mention public acceptance. Nanomaterials can be so complex that their manufacturing processes become complex, which may potentially bring into question long-term effects on human health and the environment. It discusses the current barriers to their wide application, particularly regarding regulatory hurdles and the production of robust clinical evidence.ConclusionsThis policy brief identifies key considerations for policymakers and stakeholders, highlighting the requirement for integration among researchers, clinicians, and regulatory bodies. To facilitate safe and successful integration of nanomedicines into patient care, continued collaboration are imperative. Priority in the future should be given to developing comprehensive regulatory frameworks, raising public awareness, and promoting interdisciplinary research to resolve existing challenges and unlock the potential of nanomedicines in the healthcare sector.

纳米药物在卫生保健系统中的使用:一份政策简报。
目的纳米医学是纳米技术在医学上的应用,因此是一种潜在的医疗保健变革方法。这一新兴的跨学科领域在诊断、控制/靶向药物输送和再生医学方面有三个主要应用。纳米医学通过推进各种疾病的诊断、预防和治疗,包括癌症、心血管疾病和神经系统疾病,具有改变人类健康的巨大潜力。尽管潜力巨大,但仍有一些问题阻碍了纳米药物完全整合到医疗保健系统中。本政策摘要解决了这些关键问题,为有效部署纳米医学以改善患者预后和推进重要公共卫生举措的决策提供信息和指导。此外,还对今后的发展提出了展望。这些全新的纳米系统在安全性、有效性和法规遵从性方面存在一些严重的缺陷,更不用说公众接受度了。纳米材料非常复杂,其制造过程也变得复杂,这可能会对人类健康和环境的长期影响产生疑问。它讨论了目前阻碍其广泛应用的障碍,特别是关于监管障碍和产生强有力的临床证据。本政策摘要确定了决策者和利益相关者的关键考虑因素,强调了研究人员、临床医生和监管机构之间整合的需求。为了促进安全和成功地将纳米药物整合到患者护理中,继续合作是必不可少的。未来应该优先考虑制定全面的管理框架、提高公众意识和促进跨学科研究,以解决现有的挑战并释放纳米药物在卫生保健部门的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.80
自引率
0.00%
发文量
82
审稿时长
4.5 months
期刊介绍: The aim of Drug Development and Industrial Pharmacy is to publish novel, original, peer-reviewed research manuscripts within relevant topics and research methods related to pharmaceutical research and development, and industrial pharmacy. Research papers must be hypothesis driven and emphasize innovative breakthrough topics in pharmaceutics and drug delivery. The journal will also consider timely critical review papers.
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