Editorial Expression of Concern: Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma
Satyabrata Sinha, Ratnesh K. Singh, Neyaz Alam, Anup Roy, Susanta Roychoudhury, Chinmay Kumar Panda
{"title":"Editorial Expression of Concern: Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma","authors":"Satyabrata Sinha, Ratnesh K. Singh, Neyaz Alam, Anup Roy, Susanta Roychoudhury, Chinmay Kumar Panda","doi":"10.1186/s12943-024-02181-x","DOIUrl":null,"url":null,"abstract":"<p><b>Correction: Mol Cancer 7, 84 (2008)</b></p><p><b>https://doi.org/10.1186/1476-4598-7-84</b>.</p><p> The Editor-in-Chief would like to alert the readers that concerns have been raised regarding some of the data presented in the figures. Specifically:</p><ul>\n<li>\n<p>In Fig. 1c (upper panel), the 588 T and 366 D9S104 bands appear highly similar, and the 4131 T D9S104 band appears highly similar to 3025 N PHF2 ex-18.</p>\n</li>\n<li>\n<p>In Fig. 3b, the two upper panels appear to have repetitive features in the gel backgrounds, and the bottom panel appears to have inconsistencies in the background.</p>\n</li>\n<li>\n<p>Figure 6c and f appear highly similar to Fig. 5d and a in [1], respectively.</p>\n</li>\n</ul><p> Due to the age of the article, the authors are unable to provide the underlying raw data to sufficiently address these concerns. Readers are therefore advised to interpret these results with caution.</p><p> All authors agree to this Editorial Expression of Concern.</p><ol data-track-component=\"outbound reference\" data-track-context=\"references section\"><li data-counter=\"1.\"><p>Sinha Satyabrata, Singh Ratnesh K, Nilanjana B, Nupur M, Susmita G, Neyaz A, Anup R, Susanta R, Chinmay Kumar P. Frequent alterations of LOH11CR2A, PIG8 and CHEK1 genes at chromosomal 11q24.1-24.2 region in breast carcinoma: clinical and prognostic implications. Mol Oncol. 2011;5. https://doi.org/10.1016/j.molonc.2011.06.005.</p></li></ol><p>Download references<svg aria-hidden=\"true\" focusable=\"false\" height=\"16\" role=\"img\" width=\"16\"><use xlink:href=\"#icon-eds-i-download-medium\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"></use></svg></p><h3>Authors and Affiliations</h3><ol><li><p>Department of Oncogene Regulation, Chittaranjan National Cancer Institute, Kolkata, India</p><p>Satyabrata Sinha, Ratnesh K. Singh & Chinmay Kumar Panda</p></li><li><p>Department of Surgical Oncology, Chittaranjan National Cancer Institute, Kolkata, India</p><p>Neyaz Alam</p></li><li><p>Department of Pathology, Medical College, Kolkata, India</p><p>Anup Roy</p></li><li><p>Molecular and Human Genetics Division, Indian Institute of Chemical Biology, Kolkata, India</p><p>Susanta Roychoudhury</p></li></ol><span>Authors</span><ol><li><span>Satyabrata Sinha</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Ratnesh K. Singh</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Neyaz Alam</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Anup Roy</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Susanta Roychoudhury</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Chinmay Kumar Panda</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li></ol><h3>Corresponding author</h3><p>Correspondence to Chinmay Kumar Panda.</p><h3>Publisher’s note</h3><p>Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.</p><p>The online version of the original article can be found at https://doi.org/10.1186/1476-4598-7-84.</p><p><b>Open Access</b> This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.</p>\n<p>Reprints and permissions</p><img alt=\"Check for updates. 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Expression of Concern: Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma. <i>Mol Cancer</i> <b>24</b>, 108 (2025). https://doi.org/10.1186/s12943-024-02181-x</p><p>Download citation<svg aria-hidden=\"true\" focusable=\"false\" height=\"16\" role=\"img\" width=\"16\"><use xlink:href=\"#icon-eds-i-download-medium\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"></use></svg></p><ul data-test=\"publication-history\"><li><p>Published<span>: </span><span><time datetime=\"2025-04-05\">05 April 2025</time></span></p></li><li><p>DOI</abbr><span>: </span><span>https://doi.org/10.1186/s12943-024-02181-x</span></p></li></ul><h3>Share this article</h3><p>Anyone you share the following link with will be able to read this content:</p><button data-track=\"click\" data-track-action=\"get shareable link\" data-track-external=\"\" data-track-label=\"button\" type=\"button\">Get shareable 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Abstract
Correction: Mol Cancer 7, 84 (2008)
https://doi.org/10.1186/1476-4598-7-84.
The Editor-in-Chief would like to alert the readers that concerns have been raised regarding some of the data presented in the figures. Specifically:
In Fig. 1c (upper panel), the 588 T and 366 D9S104 bands appear highly similar, and the 4131 T D9S104 band appears highly similar to 3025 N PHF2 ex-18.
In Fig. 3b, the two upper panels appear to have repetitive features in the gel backgrounds, and the bottom panel appears to have inconsistencies in the background.
Figure 6c and f appear highly similar to Fig. 5d and a in [1], respectively.
Due to the age of the article, the authors are unable to provide the underlying raw data to sufficiently address these concerns. Readers are therefore advised to interpret these results with caution.
All authors agree to this Editorial Expression of Concern.
Sinha Satyabrata, Singh Ratnesh K, Nilanjana B, Nupur M, Susmita G, Neyaz A, Anup R, Susanta R, Chinmay Kumar P. Frequent alterations of LOH11CR2A, PIG8 and CHEK1 genes at chromosomal 11q24.1-24.2 region in breast carcinoma: clinical and prognostic implications. Mol Oncol. 2011;5. https://doi.org/10.1016/j.molonc.2011.06.005.
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Authors and Affiliations
Department of Oncogene Regulation, Chittaranjan National Cancer Institute, Kolkata, India
Satyabrata Sinha, Ratnesh K. Singh & Chinmay Kumar Panda
Department of Surgical Oncology, Chittaranjan National Cancer Institute, Kolkata, India
Neyaz Alam
Department of Pathology, Medical College, Kolkata, India
Anup Roy
Molecular and Human Genetics Division, Indian Institute of Chemical Biology, Kolkata, India
Susanta Roychoudhury
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Correspondence to Chinmay Kumar Panda.
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Sinha, S., Singh, R.K., Alam, N. et al. Editorial Expression of Concern: Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma. Mol Cancer24, 108 (2025). https://doi.org/10.1186/s12943-024-02181-x
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Molecular Cancer is a platform that encourages the exchange of ideas and discoveries in the field of cancer research, particularly focusing on the molecular aspects. Our goal is to facilitate discussions and provide insights into various areas of cancer and related biomedical science. We welcome articles from basic, translational, and clinical research that contribute to the advancement of understanding, prevention, diagnosis, and treatment of cancer.
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