Squamous Cell Carcinoma of the Tonsil Unmasked by 68 Ga-FAPI-46 PET/CT.

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-10-01 Epub Date: 2025-03-28 DOI:10.1097/RLU.0000000000005866

Jiaqing Liu, Xiyi Liao, Yizhen Pang, Qin Lin, Haojun Chen

引用次数: 0

Abstract

We reported 18 F-FDG and 68 Ga-FAPI-46 PET/CT findings in a 55-year-old woman with metastatic squamous cell carcinoma of the left neck. 18 F-FDG PET/CT was negative for the detection of primary malignancy. On 68 Ga-FAPI PET/CT, increased radiotracer uptake was noted in the left palatine tonsil, whereas low background uptake was observed in the right palatine tonsil. Based on the PET/CT findings, the patient underwent clinical examination and biopsy of the left tonsil. Histology demonstrated the presence of a squamous cell carcinoma of the tonsil. The case demonstrated the added value of 68 Ga-FAPI-46 PET/CT for locating the primary malignancy in cancer of unknown primary.

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68Ga-FAPI-46 PET/CT显示扁桃体鳞状细胞癌。

我们报告了一例55岁左颈部转移性鳞状细胞癌患者的18F-FDG和68Ga-FAPI-46 PET/CT检查结果。18F-FDG PET/CT对原发性恶性肿瘤的检测为阴性。68Ga-FAPI PET/CT显示，左侧腭扁桃体放射性示踪剂摄取增加，而右侧腭扁桃体放射性示踪剂摄取低。根据PET/CT结果，患者接受了临床检查和左扁桃体活检。组织学表现为扁桃体鳞状细胞癌。本病例证明了68Ga-FAPI-46 PET/CT在原发不明的肿瘤中定位原发恶性肿瘤的附加价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.