[ 68 Ga]Ga-FAPI-46 PET/MRT Unveils Lymph Node Metastases and Changes Treatment Strategy in Recurrent Advanced High-grade Serous Ovarian Carcinoma Patient.

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-09-01 Epub Date: 2025-03-28 DOI:10.1097/RLU.0000000000005871

Marie Prochiner, Anna Hinterberger, Björn Wängler, Frederik Marmé, Freba Grawe

引用次数: 0

Abstract

High-grade serous ovarian carcinoma (HGOC) is frequently diagnosed at an advanced stage, leading to high recurrence rates. This case report highlights the utility of [ 68 Ga]Ga-FAPI-46 PET/MRI in detecting previously unidentified lymph node metastases in a 75-year-old woman with recurrent HGOC, which altered the treatment strategy. The imaging revealed increased [ 68 Ga]Ga-FAPI-46 uptake in nonenlarged mediastinal and left perihilar lymph nodes, reclassifying the patient from FIGO IIIb to FIGO stage IV and prompting a change in therapeutic management.

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[68Ga]Ga-FAPI-46 PET/MRT揭示晚期高级别浆液性卵巢癌复发患者淋巴结转移及治疗策略的改变。

高级别浆液性卵巢癌（HGOC）通常在晚期诊断，导致高复发率。本病例报告强调了[68Ga]Ga-FAPI-46 PET/MRI在检测一名75岁复发性HGOC女性先前未识别的淋巴结转移中的应用，这改变了治疗策略。影像学显示未增大的纵隔和左侧门周淋巴结[68Ga]Ga-FAPI-46摄取增加，将患者从FIGO IIIb期重新分类为FIGO IV期，并提示治疗管理的改变。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.