[Endoscopic intervention combined with pirfenidone for the treatment of cicatricial central airway stenosis: a report of 4 cases].

Abstract

A retrospective analysis of the clinical data of four patients with cicatricial central airway stenosis was performed. The study compared the intervals between interventional treatments, the airway diameter before interventional treatment, and the dyspnea index scores of the patients before and after the use of pirfenidone. The results showed that the intervals between interventional treatments were significantly prolonged in two patients, the airway diameters before interventional treatment were significantly increased and the symptoms of dyspnea were improved in all four patients. In addition, the number of interventional treatments was reduced. This study suggested that pirfenidone might have therapeutic potential in cicatricial central airway stenosis.