{"title":"[Management of migraine without aura in adolescents: The experience of flunarizine use in a Turkish cohort].","authors":"Faik Ilik, Devrimsel Harika Ertem, M Kemal Ilik","doi":"10.18071/isz.77.0122","DOIUrl":null,"url":null,"abstract":"<p><strong>Background and purpose: </strong>Flunarizine is a specific calcium antagonist and is frequently used in adults for the prophylactic treatment of migraine. The use of flunarizine may lead to somnolence and weight gain, depression, and rarely extrapyramidal symptoms in adults. However, studies detecting the efficacy and safety of flunarizine use in adolescents are limited. In the current study, the effectiveness of flunarizine for the management of migraine without aura in Turkish adolescents was evaluated.</p><p><strong>Methods: </strong>Forty-six patients with migraine without aura, receiving flunarizine 5mg per day were included. In this retrospective study, the medical records of the cases were examined. Visual Analog Scale (VAS) and MIDAS scores were compared to assess the efficacy of the 3 months treatment.</p><p><strong>Results: </strong>The mean age was 14.37±1.83 years. There was a significant improvement in the VAS and MIDAS scores of the patients at the end of the third month (p.</p><p><strong>Conclusion: </strong>Although the advancement of migraine research and treatment is inevitable, our findings support that flunarizine should still be considered as an effective and tolerable treatment option in adolescent migraineurs.</p>","PeriodicalId":50394,"journal":{"name":"Ideggyogyaszati Szemle-Clinical Neuroscience","volume":"78 3-04","pages":"122-126"},"PeriodicalIF":0.9000,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ideggyogyaszati Szemle-Clinical Neuroscience","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.18071/isz.77.0122","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background and purpose: Flunarizine is a specific calcium antagonist and is frequently used in adults for the prophylactic treatment of migraine. The use of flunarizine may lead to somnolence and weight gain, depression, and rarely extrapyramidal symptoms in adults. However, studies detecting the efficacy and safety of flunarizine use in adolescents are limited. In the current study, the effectiveness of flunarizine for the management of migraine without aura in Turkish adolescents was evaluated.
Methods: Forty-six patients with migraine without aura, receiving flunarizine 5mg per day were included. In this retrospective study, the medical records of the cases were examined. Visual Analog Scale (VAS) and MIDAS scores were compared to assess the efficacy of the 3 months treatment.
Results: The mean age was 14.37±1.83 years. There was a significant improvement in the VAS and MIDAS scores of the patients at the end of the third month (p.
Conclusion: Although the advancement of migraine research and treatment is inevitable, our findings support that flunarizine should still be considered as an effective and tolerable treatment option in adolescent migraineurs.
期刊介绍：
The aim of Clinical Neuroscience (Ideggyógyászati Szemle) is to provide a forum for the exchange of clinical and scientific information for a multidisciplinary community. The Clinical Neuroscience will be of primary interest to neurologists, neurosurgeons, psychiatrist and clinical specialized psycholigists, neuroradiologists and clinical neurophysiologists, but original works in basic or computer science, epidemiology, pharmacology, etc., relating to the clinical practice with involvement of the central nervous system are also welcome.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
