[Management of migraine without aura in adolescents: The experience of flunarizine use in a Turkish cohort].

IF 0.9 4区医学 Q4 CLINICAL NEUROLOGY

Ideggyogyaszati Szemle-Clinical Neuroscience Pub Date : 2025-03-30 DOI:10.18071/isz.77.0122

Faik Ilik, Devrimsel Harika Ertem, M Kemal Ilik

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引用次数: 0

Abstract

Background and purpose: Flunarizine is a specific calcium antagonist and is frequently used in adults for the prophylactic treatment of migraine. The use of flunarizine may lead to somnolence and weight gain, depression, and rarely extrapyramidal symptoms in adults. However, studies detecting the efficacy and safety of flunarizine use in adolescents are limited. In the current study, the effectiveness of flunarizine for the management of migraine without aura in Turkish adolescents was evaluated.

Methods: Forty-six patients with migraine without aura, receiving flunarizine 5mg per day were included. In this retrospective study, the medical records of the cases were examined. Visual Analog Scale (VAS) and MIDAS scores were compared to assess the efficacy of the 3 months treatment.

Results: The mean age was 14.37±1.83 years. There was a significant improvement in the VAS and MIDAS scores of the patients at the end of the third month (p.

Conclusion: Although the advancement of migraine research and treatment is inevitable, our findings support that flunarizine should still be considered as an effective and tolerable treatment option in adolescent migraineurs.

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[青少年无先兆偏头痛的治疗：氟桂利嗪在土耳其队列中的应用经验]。

背景和目的：氟桂利嗪是一种特异性钙拮抗剂，常用于成人偏头痛的预防性治疗。使用氟桂利嗪可导致嗜睡、体重增加、抑郁，成人很少出现锥体外系症状。然而，检测氟桂利嗪在青少年使用的有效性和安全性的研究是有限的。在目前的研究中，氟桂利嗪对治疗土耳其青少年无先兆偏头痛的有效性进行了评估。方法：选取46例无先兆偏头痛患者，服用氟桂利嗪5mg / d。在本回顾性研究中，检查了病例的医疗记录。比较视觉模拟评分（VAS）和MIDAS评分，评估3个月治疗的疗效。结果：平均年龄14.37±1.83岁。结论：尽管偏头痛研究和治疗的进步是不可避免的，但我们的研究结果支持氟桂利嗪仍应被视为青少年偏头痛的有效和可耐受的治疗选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ideggyogyaszati Szemle-Clinical Neuroscience CLINICAL NEUROLOGY-NEUROSCIENCES

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The aim of Clinical Neuroscience (Ideggyógyászati Szemle) is to provide a forum for the exchange of clinical and scientific information for a multidisciplinary community. The Clinical Neuroscience will be of primary interest to neurologists, neurosurgeons, psychiatrist and clinical specialized psycholigists, neuroradiologists and clinical neurophysiologists, but original works in basic or computer science, epidemiology, pharmacology, etc., relating to the clinical practice with involvement of the central nervous system are also welcome.