Can we talk? The cryptic communications of hepatic stellate cells in lipid metabolism

IF 27.7 1区生物学 Q1 CELL BIOLOGY

Cell metabolism Pub Date : 2025-04-01 DOI:10.1016/j.cmet.2025.03.008

Scott L. Friedman

引用次数: 0

Abstract

The contributions of signals generated by hepatic stellate cells that regulate hepatocyte lipid and glucose homeostasis are largely unexplored. The article by Hansen et al. introduces a novel role of plasmalemma vesicle-associated protein (PLVAP), a membrane protein expressed by hepatic stellate cells, in regulating these pathways in hepatocytes during fasting.

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我们能谈谈吗？肝星状细胞在脂质代谢中的隐性通讯

肝星状细胞产生的调节肝细胞脂质和葡萄糖稳态的信号的贡献在很大程度上尚未被探索。Hansen等人的文章介绍了质膜囊泡相关蛋白（PLVAP）的新作用，这是一种由肝星状细胞表达的膜蛋白，在禁食期间调节肝细胞的这些途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell metabolism 生物-内分泌学与代谢

CiteScore

48.60

自引率

1.40%

发文量

173

审稿时长

2.5 months

期刊介绍： Cell Metabolism is a top research journal established in 2005 that focuses on publishing original and impactful papers in the field of metabolic research.It covers a wide range of topics including diabetes, obesity, cardiovascular biology, aging and stress responses, circadian biology, and many others. Cell Metabolism aims to contribute to the advancement of metabolic research by providing a platform for the publication and dissemination of high-quality research and thought-provoking articles.