{"title":"Multiple gingival recession coverage using indigenously prepared amnion-chorion membrane: a clinical study.","authors":"Supriya Jain, Arundeep Kaur Lamba, Farrukh Faraz, Shruti Tandon, Archita Datta, Sachin Dhingra","doi":"10.1007/s10561-025-10169-0","DOIUrl":null,"url":null,"abstract":"<p><p>A prospective clinical study was conducted to evaluate the effectiveness of indigenously prepared amnion-chorion membrane for the management of multiple adjacent gingival recession. 15 healthy subjects, 8 female and 7 male ranging in age from 18 to 55 years, with maxillary anterior and premolar gingival recession defects were included and all the subjects were treated with the Zucchelli technique along with the placement of amnion-chorion membrane. Clinical examination post-surgery revealed healthy gingival tissues with color and texture blending with adjacent tissues. Complete root coverage was obtained in 44 out of a total of 52 sites with percentage mean root coverage accounting to 97.77%. Also, a statistically significant increase in the width and thickness of keratinized tissue was observed (p < 0.01). Long-term, multicentric, randomized controlled clinical trials with a larger sample size are needed in the future to confirm the findings of the present study and explore the potential of amnion-chorion membrane for its use in regenerative periodontics.</p>","PeriodicalId":9723,"journal":{"name":"Cell and Tissue Banking","volume":"26 2","pages":"20"},"PeriodicalIF":1.4000,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell and Tissue Banking","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1007/s10561-025-10169-0","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
A prospective clinical study was conducted to evaluate the effectiveness of indigenously prepared amnion-chorion membrane for the management of multiple adjacent gingival recession. 15 healthy subjects, 8 female and 7 male ranging in age from 18 to 55 years, with maxillary anterior and premolar gingival recession defects were included and all the subjects were treated with the Zucchelli technique along with the placement of amnion-chorion membrane. Clinical examination post-surgery revealed healthy gingival tissues with color and texture blending with adjacent tissues. Complete root coverage was obtained in 44 out of a total of 52 sites with percentage mean root coverage accounting to 97.77%. Also, a statistically significant increase in the width and thickness of keratinized tissue was observed (p < 0.01). Long-term, multicentric, randomized controlled clinical trials with a larger sample size are needed in the future to confirm the findings of the present study and explore the potential of amnion-chorion membrane for its use in regenerative periodontics.
期刊介绍：
Cell and Tissue Banking provides a forum for disseminating information to scientists and clinicians involved in the banking and transplantation of cells and tissues. Cell and Tissue Banking is an international, peer-reviewed journal that publishes original papers in the following areas:
basic research concerning general aspects of tissue banking such as quality assurance and control of banked cells/tissues, effects of preservation and sterilisation methods on cells/tissues, biotechnology, etc.; clinical applications of banked cells/tissues; standards of practice in procurement, processing, storage and distribution of cells/tissues; ethical issues; medico-legal issues.
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