Zelsuvmi Berdazimer—A Novel New Therapy for Molluscum Contagiosum—Efficacy, Safety, and Future Considerations

Jawairya Muhammad Hussain, Sameen Suhail, Saim Mahmood Khan, Abdul Wasio
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Abstract

Berdazimer sodium, marketed as Zelsuvmi, is an antiviral medication used to treat a viral infection called molluscum contagiosum (MC). MC is a common skin infection caused by a poxvirus, resulting in round, stiff, but painless papules in various places on the body. Zelsuvmi's antiviral activity is associated with the release of nitric oxide, which exhibits potent antiviral properties. Zelsuvmi is used topically by patients or caregivers to treat this extremely contagious viral skin infection at home or in medical facilities. On January 5, 2024, the U.S. Food and Drug Administration approved Zelsuvmi for treating this infection in target populations, including adults and patients aged 1 year and above. Other therapies for MC, such as retinoic acid, benzoyl peroxide, and cryotherapy, are quite painful, while Zelsuvmi is less painful. The purpose of this article is to highlight the clinical importance and potential benefits of Zelsuvmi in the treatment of MC worldwide.

Abstract Image

Zelsuvmi berdazimer——一种治疗传染性软疣的新疗法——疗效、安全性和未来的考虑
Berdazimer钠,以Zelsuvmi销售,是一种抗病毒药物,用于治疗一种叫做传染性软疣(MC)的病毒感染。MC是一种常见的皮肤感染,由痘病毒引起,导致身体各处出现圆形,僵硬但无痛的丘疹。Zelsuvmi的抗病毒活性与一氧化氮的释放有关,一氧化氮表现出强大的抗病毒特性。Zelsuvmi是患者或护理人员在家中或医疗机构治疗这种极具传染性的病毒性皮肤感染的局部用药。2024年1月5日,美国食品和药物管理局批准Zelsuvmi用于治疗目标人群中的这种感染,包括成人和1岁及以上的患者。其他治疗MC的方法,如视黄酸、过氧化苯甲酰和冷冻疗法,都是相当痛苦的,而Zelsuvmi则不那么痛苦。本文的目的是强调Zelsuvmi在全球范围内治疗MC的临床重要性和潜在益处。
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