Identification of DICER1 Syndrome on the Basis of Familial, Early-Onset Differentiated Thyroid Cancer

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL

Clinical Case Reports Pub Date : 2025-03-28 DOI:10.1002/ccr3.70295

Jessica Y. Wong, Alex Henderson, Simon Harper, Richard W. Carroll, Peter B. Bethwaite, Esko Wiltshire

引用次数: 0

Abstract

DICER1 syndrome encompasses a wide range of phenotypes, and not all individuals with DICER1 syndrome develop aggressive soft tissue tumors. DICER1 syndrome and other genetic conditions predisposing to the development of thyroid tumors should be considered when a young patient presents with thyroid nodules and a positive family history.

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家族性早发分化型甲状腺癌DICER1综合征的鉴定

DICER1综合征包括多种表型，并非所有DICER1综合征患者都会患侵袭性软组织肿瘤。当年轻患者出现甲状腺结节并有阳性家族史时，应考虑DICER1综合征和其他易患甲状腺肿瘤的遗传病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Case Reports MEDICINE, GENERAL & INTERNAL-

自引率

14.30%

发文量

1268

审稿时长

13 weeks

期刊介绍： Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).