Free Flap Surgery and Oncologic Care of the Pregnant Head and Neck Cancer Patient.

IF 2.3 3区医学 Q1 OTORHINOLARYNGOLOGY

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2025-03-27 DOI:10.1002/hed.28142

Sida Chen, Ricardo J Ramirez, Mohemmed N Khan, Mark L Urken, Yara Sifri, Jill A Berkin, Scott A Roof

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Abstract

Background: Although head and neck cancer (HNC) in pregnant patients is rare, the incidence of oral cavity cancer has increased in younger women of childbearing age. We detail the complexities of two cases of HNC during pregnancy requiring surgical resection with free flap reconstruction, followed by general guidelines for HNC care of this population.

Methods: We report two cases of head and neck cancer management in the pregnant patient.

Results: Both patients underwent similar free flap reconstruction for oral cavity cancer. One was able to avoid adjuvant and deliver a healthy child at term, while the second required early termination followed by chemotherapy and radiation. Both remain disease free.

Conclusions: Multidisciplinary management is crucial in care for the pregnant HNC patient. Goals include cumulative radiation dose exposures below 100 mGy, operating in the second trimester when the risk is lowest to the fetus and mother, and avoiding chemotherapy or radiation in the first trimester when possible.

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妊娠头颈癌患者的游离皮瓣手术及肿瘤护理。

背景：虽然头颈癌（HNC）在怀孕患者中很少见，但口腔癌的发病率在较年轻的育龄妇女中有所增加。我们详细介绍了两例妊娠期HNC的复杂性，需要手术切除并进行游离皮瓣重建，然后是该人群HNC护理的一般指南。方法：我们报告了2例头颈癌孕妇的治疗。结果：两例口腔癌患者均行相似的游离皮瓣重建。其中一种能够避免辅助治疗并在足月生下健康的孩子，而另一种则需要在化疗和放疗后早期终止妊娠。两者都没有患病。结论：多学科管理对妊娠HNC患者的护理至关重要。目标包括累积辐射剂量低于100毫戈瑞，在对胎儿和母亲的风险最低的妊娠中期进行手术，并在妊娠早期尽可能避免化疗或放疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 医学-耳鼻喉科学

CiteScore

7.00

自引率

6.90%

发文量

278

审稿时长

1.6 months

期刊介绍： Head & Neck is an international multidisciplinary publication of original contributions concerning the diagnosis and management of diseases of the head and neck. This area involves the overlapping interests and expertise of several surgical and medical specialties, including general surgery, neurosurgery, otolaryngology, plastic surgery, oral surgery, dermatology, ophthalmology, pathology, radiotherapy, medical oncology, and the corresponding basic sciences.