{"title":"Fracture-Related Infections.","authors":"Jessica Seidelman, Malcolm DeBaun","doi":"10.1016/j.idc.2025.02.012","DOIUrl":null,"url":null,"abstract":"<p><p>Fracture-related infections are challenging complications in orthopedic care, marked by infection at fracture or surgical sites, often involving biofilm-associated pathogens. They result in significant morbidity, prolonged hospitalizations, and high health care costs. Diagnosis integrates clinical, laboratory, and imaging findings, while treatment combines surgical debridement, implant management, and targeted antimicrobial therapy. Common pathogens include Staphylococcus aureus and Staphylococcus epidermidis, with culture-negative cases requiring advanced diagnostics. A multidisciplinary approach is critical to optimizing outcomes, addressing complications, and reducing the socioeconomic impact of these infections. Advances in treatment strategies continue to improve survival and quality of life for affected patients.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":6.1000,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infectious disease clinics of North America","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.idc.2025.02.012","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Fracture-related infections are challenging complications in orthopedic care, marked by infection at fracture or surgical sites, often involving biofilm-associated pathogens. They result in significant morbidity, prolonged hospitalizations, and high health care costs. Diagnosis integrates clinical, laboratory, and imaging findings, while treatment combines surgical debridement, implant management, and targeted antimicrobial therapy. Common pathogens include Staphylococcus aureus and Staphylococcus epidermidis, with culture-negative cases requiring advanced diagnostics. A multidisciplinary approach is critical to optimizing outcomes, addressing complications, and reducing the socioeconomic impact of these infections. Advances in treatment strategies continue to improve survival and quality of life for affected patients.
期刊介绍：
Infectious Disease Clinics of North America updates you on the latest trends in the clinical diagnosis and management of patients with infectious diseases, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Each issue focuses on a single topic in infectious disease, including clinical microbiology, compromised host infections, gastrointestinal infections, global health, hepatitis, HIV/AIDS, hospital-acquired infections, travel medicine, infection control, bacterial infections, sexually transmitted diseases, urinary tract infections, and viral infections.
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