{"title":"MXene-Based Electrochemical Biosensors: Advancing Detection Strategies for Biosensing (2020-2024).","authors":"Joydip Sengupta, Chaudhery Mustansar Hussain","doi":"10.3390/bios15030127","DOIUrl":null,"url":null,"abstract":"<p><p>MXenes, a class of two-dimensional materials, have emerged as promising candidates for developing advanced electrochemical biosensors due to their exceptional electrical conductivity, large surface area, and rich surface chemistry. These unique properties enable high sensitivity, rapid response, and versatile functionalization, making MXene-based biosensors highly suitable for detecting biomolecules and pathogens in biomedical applications. This review explores recent advancements in MXene-based electrochemical biosensors from 2020 to 2024, focusing on their design principles, fabrication strategies, and integration with microfluidic platforms for enhanced performance. The potential of MXene sensors to achieve real-time and multiplexed detection is highlighted, alongside the associated challenges. Emphasis is placed on the role of MXenes in addressing critical needs in disease diagnostics, personalized medicine, and point-of-care testing, providing insights into future trends and transformative possibilities in the field of biomedical sensing technologies.</p>","PeriodicalId":48608,"journal":{"name":"Biosensors-Basel","volume":"15 3","pages":""},"PeriodicalIF":4.9000,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11940519/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biosensors-Basel","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.3390/bios15030127","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
MXenes, a class of two-dimensional materials, have emerged as promising candidates for developing advanced electrochemical biosensors due to their exceptional electrical conductivity, large surface area, and rich surface chemistry. These unique properties enable high sensitivity, rapid response, and versatile functionalization, making MXene-based biosensors highly suitable for detecting biomolecules and pathogens in biomedical applications. This review explores recent advancements in MXene-based electrochemical biosensors from 2020 to 2024, focusing on their design principles, fabrication strategies, and integration with microfluidic platforms for enhanced performance. The potential of MXene sensors to achieve real-time and multiplexed detection is highlighted, alongside the associated challenges. Emphasis is placed on the role of MXenes in addressing critical needs in disease diagnostics, personalized medicine, and point-of-care testing, providing insights into future trends and transformative possibilities in the field of biomedical sensing technologies.
Biosensors-BaselBiochemistry, Genetics and Molecular Biology-Clinical Biochemistry
CiteScore
6.60
自引率
14.80%
发文量
983
审稿时长
11 weeks
期刊介绍:
Biosensors (ISSN 2079-6374) provides an advanced forum for studies related to the science and technology of biosensors and biosensing. It publishes original research papers, comprehensive reviews and communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Electronic files and software regarding the full details of the calculation or experimental procedure, if unable to be published in a normal way, can be deposited as supplementary electronic material.