Transcription Factors in Biocontrol Fungi.

Abstract

Transcription factors are extensively found in fungi and are involved in the regulation of multiple biological processes, including growth, development, conidiation, morphology, stresses tolerance, and virulence, as well as the production of secondary metabolites. Biocontrol is a complex biological process through which several biocontrol behaviors, such as the secretion of cell wall-degrading enzymes and the production of secondary metabolites, are regulated by transcription factors. To date, biocontrol-related transcription factors have been reported in several biocontrol fungi, such as Beauveria bassiana, Clonostachys rosea, Coniothyrium minitans, and different species in the genera Metarhizium, Trichoderma, and Arthrobotrys. However, comprehensive reviews summarizing and analyzing transcription factors with biocontrol potential in these fungi are scarce. This review begins by giving a basic overview of transcription factors and their functions. Then, the role of biocontrol-related transcription factors in biocontrol fungi is discussed. Lastly, possible approaches for further work on transcription factors in biocontrol fungi are suggested. This review provides a basis for further elaborating the molecular mechanisms of transcription factors in the context of biocontrol.