Aging-induced Alternation in the Gut Microbiota Impairs Host Antibacterial Defense (Adv. Sci. 12/2025)

IF 14.3 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Advanced Science Pub Date : 2025-03-27 DOI:10.1002/advs.202570084

Peng Gu, Rongjuan Wei, Ruofan Liu, Qin Yang, Yuxuan He, Jianbin Guan, Wenhao He, Jiaxin Li, Yunfei Zhao, Li Xie, Jie He, Qingling Guo, Jiajia Hu, Jingna Bao, Wandang Wang, Jiayin Guo, Zhenhua Zeng, Zhongqing Chen, Yong Jiang, Zhanguo Liu, Peng Chen

{"title":"Aging-induced Alternation in the Gut Microbiota Impairs Host Antibacterial Defense (Adv. Sci. 12/2025)","authors":"Peng Gu, Rongjuan Wei, Ruofan Liu, Qin Yang, Yuxuan He, Jianbin Guan, Wenhao He, Jiaxin Li, Yunfei Zhao, Li Xie, Jie He, Qingling Guo, Jiajia Hu, Jingna Bao, Wandang Wang, Jiayin Guo, Zhenhua Zeng, Zhongqing Chen, Yong Jiang, Zhanguo Liu, Peng Chen","doi":"10.1002/advs.202570084","DOIUrl":null,"url":null,"abstract":"<p><b>Antibacterial Defense</b></p><p>In article number 2411008, Yong Jiang, Zhanguo Liu, Peng Chen, and co-workers investigate the role of gut microbiota in antibacterial defense of older adults, identifying apigenin derived from Parabacteroides goldsteinii as a key factor in ameliorating aging-associated antibacterial defects. This cover illustration depicts an ancient Chinese mythological story in which Ne Zha rescues Jiang Ziya from perilous flames. Ne Zha, symbolizing Parabacteroides goldsteinii, waves chaotic silk representing apigenin to protect Jiang Ziya, who signifies older adults.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":"12 12","pages":""},"PeriodicalIF":14.3000,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/advs.202570084","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Science","FirstCategoryId":"88","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/advs.202570084","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

Antibacterial Defense

In article number 2411008, Yong Jiang, Zhanguo Liu, Peng Chen, and co-workers investigate the role of gut microbiota in antibacterial defense of older adults, identifying apigenin derived from Parabacteroides goldsteinii as a key factor in ameliorating aging-associated antibacterial defects. This cover illustration depicts an ancient Chinese mythological story in which Ne Zha rescues Jiang Ziya from perilous flames. Ne Zha, symbolizing Parabacteroides goldsteinii, waves chaotic silk representing apigenin to protect Jiang Ziya, who signifies older adults.

Abstract Image

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Advanced Science CHEMISTRY, MULTIDISCIPLINARYNANOSCIENCE &-NANOSCIENCE & NANOTECHNOLOGY

CiteScore

18.90

自引率

2.60%

发文量

1602

审稿时长

1.9 months

期刊介绍： Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.