{"title":"Conjunctival Silicone Granuloma From Breast Implants.","authors":"Anna J Sun, Anna M Stagner, Han-Ying P Chang","doi":"10.1097/ICO.0000000000003866","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this report was to highlight a case of migratory conjunctival silicone granuloma formation years after silicone breast implantation.</p><p><strong>Methods: </strong>A 65-year-old woman with history of silicone breast implant placement presented with an elevated yellow lesion on the bulbar conjunctiva. Anterior segment optical coherence tomography showed subepithelial cystic spaces. Excisional biopsy demonstrated silicone granulomata.</p><p><strong>Results: </strong>After conjunctival biopsy with amniotic membrane reconstruction, her conjunctiva healed nicely and there was no residual visible lesion.</p><p><strong>Conclusions: </strong>This case report contributes to our current understanding of the possibility of silicone migration from a distant implant site to the ocular adnexa, specifically the conjunctiva. It is important for corneal specialists and general ophthalmologists to gather a history of exogenous silicone use that could trigger systemic inflammatory responses and granuloma formation distant from the original site of silicone injection or implantation.</p>","PeriodicalId":10710,"journal":{"name":"Cornea","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cornea","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/ICO.0000000000003866","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: The purpose of this report was to highlight a case of migratory conjunctival silicone granuloma formation years after silicone breast implantation.
Methods: A 65-year-old woman with history of silicone breast implant placement presented with an elevated yellow lesion on the bulbar conjunctiva. Anterior segment optical coherence tomography showed subepithelial cystic spaces. Excisional biopsy demonstrated silicone granulomata.
Results: After conjunctival biopsy with amniotic membrane reconstruction, her conjunctiva healed nicely and there was no residual visible lesion.
Conclusions: This case report contributes to our current understanding of the possibility of silicone migration from a distant implant site to the ocular adnexa, specifically the conjunctiva. It is important for corneal specialists and general ophthalmologists to gather a history of exogenous silicone use that could trigger systemic inflammatory responses and granuloma formation distant from the original site of silicone injection or implantation.
期刊介绍：
For corneal specialists and for all general ophthalmologists with an interest in this exciting subspecialty, Cornea brings together the latest clinical and basic research on the cornea and the anterior segment of the eye. Each volume is peer-reviewed by Cornea''s board of world-renowned experts and fully indexed in archival format. Your subscription brings you the latest developments in your field and a growing library of valuable professional references.
Sponsored by The Cornea Society which was founded as the Castroviejo Cornea Society in 1975.
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