Phytochemical Investigation, Antibacterial and Antioxidant Activity Determination of Leaf Extracts of Cynoglossum coeruleum (Shimgigit).

IF 3.1 4区 生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY
Tsegaye Atnaf Chekol, Belete Bedemo Beyene, Addisu Taddele Teshale, Shewa Getachew Mamo
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引用次数: 0

Abstract

The leaf of Cynoglossum coeruleum is traditionally used in tropical medicine for treating various ailments. This study analyzed the phytochemicals, flavonoid and phenolic content, antioxidant capacity, and antibacterial activity of its leaf extracts. Phytochemical tests revealed the presence of alkaloids, flavonoids, phenols, steroids, terpenoids, and saponins. The total flavonoid content in methanol, ethyl acetate, and petroleum ether extracts was 74.66 mgQE/g, 67.34 mgQE/g, and 15.39 mgQE/g, respectively. Total phenolic content was 61.93 mg GAE/g, 25.61 mg GAE/g, and 17.72 mg GAE/g. The extracts showed significant antibacterial activity against Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Staphylococcus epidermidis at higher concentrations.

金棘叶提取物的植物化学研究、抗菌及抗氧化活性测定。
蓝棘草的叶子传统上在热带医学中用于治疗各种疾病。本研究分析了其叶提取物的植物化学成分、类黄酮和酚类物质含量、抗氧化能力和抗菌活性。植物化学测试显示生物碱、类黄酮、酚类、类固醇、萜类和皂苷的存在。甲醇、乙酸乙酯和石油醚提取物的总黄酮含量分别为74.66 mgQE/g、67.34 mgQE/g和15.39 mgQE/g。总酚含量分别为61.93 mg GAE/g、25.61 mg GAE/g和17.72 mg GAE/g。提取物在较高浓度下对大肠杆菌、肺炎克雷伯菌、金黄色葡萄球菌和表皮葡萄球菌具有显著的抑菌活性。
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来源期刊
Applied Biochemistry and Biotechnology
Applied Biochemistry and Biotechnology 工程技术-生化与分子生物学
CiteScore
5.70
自引率
6.70%
发文量
460
审稿时长
5.3 months
期刊介绍: This journal is devoted to publishing the highest quality innovative papers in the fields of biochemistry and biotechnology. The typical focus of the journal is to report applications of novel scientific and technological breakthroughs, as well as technological subjects that are still in the proof-of-concept stage. Applied Biochemistry and Biotechnology provides a forum for case studies and practical concepts of biotechnology, utilization, including controls, statistical data analysis, problem descriptions unique to a particular application, and bioprocess economic analyses. The journal publishes reviews deemed of interest to readers, as well as book reviews, meeting and symposia notices, and news items relating to biotechnology in both the industrial and academic communities. In addition, Applied Biochemistry and Biotechnology often publishes lists of patents and publications of special interest to readers.
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