Kim Madundo, Godwin Nnko, Leila Mwakipunda, Glory Makupa, Furaha Serventi
{"title":"Onset of tics in an elderly patient undergoing androgen deprivation therapy for prostate cancer: a case report.","authors":"Kim Madundo, Godwin Nnko, Leila Mwakipunda, Glory Makupa, Furaha Serventi","doi":"10.1093/omcr/omae206","DOIUrl":null,"url":null,"abstract":"<p><p>Motor and vocal tics typically manifest during childhood. Less often, tics can occur due to the use of substances or medications which raise dopamine levels. This case report describes an unusual occurrence of tics in an elderly man undergoing androgen deprivation with Goserelin for prostate cancer. Comprehensive assessments ruled out infectious, metabolic, psychiatric, and neurological conditions. The tics resolved with low-dose Risperidone, without adverse effects. This case underscores the potential for medication-induced tics in older adults, highlighting the need for increased awareness among healthcare providers regarding the neuropsychiatric effects of cancer therapies. Future research should further investigate these phenomena and their implications for treatment strategies.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 3","pages":"omae206"},"PeriodicalIF":0.5000,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924399/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oxford Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/omcr/omae206","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Motor and vocal tics typically manifest during childhood. Less often, tics can occur due to the use of substances or medications which raise dopamine levels. This case report describes an unusual occurrence of tics in an elderly man undergoing androgen deprivation with Goserelin for prostate cancer. Comprehensive assessments ruled out infectious, metabolic, psychiatric, and neurological conditions. The tics resolved with low-dose Risperidone, without adverse effects. This case underscores the potential for medication-induced tics in older adults, highlighting the need for increased awareness among healthcare providers regarding the neuropsychiatric effects of cancer therapies. Future research should further investigate these phenomena and their implications for treatment strategies.
期刊介绍：
Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.
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