{"title":"Taking a BiTE out of cancer.","authors":"Kimberly D Malkowski","doi":"10.1097/NSG.0000000000000172","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>Tarlatamab (tarlatamab-dlle) is the first bispecific T-cell engager (BiTE) therapy approved for treating a solid tumor, specifically small cell lung cancer, making it the first of its kind. It targets delta-like ligand 3 antigens on the surface of tumor cells while activating the patient's T cells. This article discusses BiTE therapy as well as its boxed warnings and precautions that nurses need to know to provide optimum patient care.</p>","PeriodicalId":35641,"journal":{"name":"Nursing","volume":"55 4","pages":"46-49"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nursing","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/NSG.0000000000000172","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/24 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"Nursing","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract: Tarlatamab (tarlatamab-dlle) is the first bispecific T-cell engager (BiTE) therapy approved for treating a solid tumor, specifically small cell lung cancer, making it the first of its kind. It targets delta-like ligand 3 antigens on the surface of tumor cells while activating the patient's T cells. This article discusses BiTE therapy as well as its boxed warnings and precautions that nurses need to know to provide optimum patient care.
期刊介绍:
Nursing2020 (ISSN 0360-4039; online ISSN 1538-8689) published its first issue in November 1971, under founders Gene W. Jackson and Daniel Cheney. In the intervening years, its circulation has grown to over 150,000, making it one of the largest nursing journals in the world. Published monthly, Nursing2020 is widely regarded as offering current, practical contents to its readers, and has won many editorial awards testifying to the quality of its copy and graphics. The editorial and clinical staff, a 19-member Editorial Board of distinguished clinicians and practitioners, and over 100 invited reviewers help ensure the quality of this publication.