Danny Mohama, Pitchaya Worapongsatitaya, Bettia Celestin, Felipe Kazmirczak, Shadi P Bagherzadeh, Kurt W Prins, Sasha Z Prisco, E Kenneth Weir, Roham Zamanian, Francois Haddad, Thenappan Thenappan
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引用次数: 0
Abstract
Pulmonary arterial hypertension (PAH) guidelines advocate measures of area for right atrial (RA) dimensions, while echocardiographic guidelines recommend RA volume. We compared the prognostic value of RA echocardiographic parameters to predict transplant-free survival in 332 adult patients with PAH. RA area correlated strongly with volume (r = 0.96). After adjusting for age and sex, for every 1-standardized unit increase in RA area index, volume index, and major axis dimension, there were 21%, 18%, and 18% higher hazards of mortality or transplant, respectively. However, no RA parameter was independently associated with transplant-free survival when adjusted for Registry to Evaluate Early and Long-Term PAH Disease Management lite score. RA area index had the highest area under the curve for predicting transplant-free survival.
期刊介绍：
The Journal of Heart and Lung Transplantation, the official publication of the International Society for Heart and Lung Transplantation, brings readers essential scholarly and timely information in the field of cardio-pulmonary transplantation, mechanical and biological support of the failing heart, advanced lung disease (including pulmonary vascular disease) and cell replacement therapy. Importantly, the journal also serves as a medium of communication of pre-clinical sciences in all these rapidly expanding areas.
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