Yugyeong Lee, Ji Su Hwang, Ziliang Zhai, Kyungwon Park, Ye Seul Son, Dae-Soo Kim, Seok Chung, Sejoong Kim, Mi-Young Son, Gwang Lee, Sungsu Park
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Abstract
This article highlights the development of apical-out tubuloids that accurately mimic drug transport mechanisms. These tubuloids exhibit selective albumin internalization, heightened sensitivity to apically transported colistin, and reduced sensitivity to basally transported tenofovir. Their ability to replicate directional drug transport offers valuable insights into drug delivery and testing models (e697).
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